Engineering mesenchymal stem cells for regenerative medicine and drug delivery
نویسندگان
چکیده
منابع مشابه
Adult mesenchymal stem cells for tissue engineering versus regenerative medicine.
Adult mesenchymal stem cells (MSCs) can be isolated from bone marrow or marrow aspirates and because they are culture-dish adherent, they can be expanded in culture while maintaining their multipotency. The MSCs have been used in preclinical models for tissue engineering of bone, cartilage, muscle, marrow stroma, tendon, fat, and other connective tissues. These tissue-engineered materials show ...
متن کاملAdult Mesenchymal Stem Cells for Tissue Engineering
The identification of multipotential mesenchymal stem cells (MSCs) derived from adult human tissues such as bone marrow and connective tissues has provided exciting prospects for cell-based tissue engineering and regeneration. This review article focuses on the biology of MSCs, their differentiation potentials in vitro and in vivo, and their application in tissue engineering...
متن کاملSpecial Issue: Mesenchymal Stem Cells Mini Review Regenerative medicine for bone diseases using mesenchymal stem cells
Since the monumental publication in 1998 by Pittenger et al., mesenchymal stem cells (MSCs) have been a center player of regenerative medicine and now a number of clinical trials using MSCs have been conducted in various fields of tissue regeneration including those of bone. It cannot be denied that due to enthusiastic clinical demanding, clinical application of MSCs has launched with little kn...
متن کاملTissue engineering stem cells, and cloning: opportunities for regenerative medicine.
Introduction to Tissue Engineering As one of the major components of regenerative medicine, tissue engineering follows the principles of cell transplantation, materials science, and engineering toward the development of biologic substitutes that can restore and maintain normal function. Tissue engineering strategies generally fall into two categories: acellular matrices, where matrices are used...
متن کاملMesenchymal Stem Cells Subpopulations: Application for Orthopedic Regenerative Medicine
Research on mesenchymal stem cells (MSCs) continues to progress rapidly. Nevertheless, the field faces several challenges, such as inherent cell heterogeneity and the absence of unique MSCs markers. Due to MSCs' ability to differentiate into multiple tissues, these cells represent a promising tool for new cell-based therapies. However, for tissue engineering applications, it is critical to star...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Methods
سال: 2015
ISSN: 1046-2023
DOI: 10.1016/j.ymeth.2015.03.002